Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409396 | 0.90 | HTR2A (0.49) | HTR2ADRD3DRD2MAPTTSHR | |
| SCHEMBL9409500 | 0.86 | HDAC4 (0.48) | HTR2ADRD3DRD2LMNAKDM4E | |
| SCHEMBL9409398 | 0.83 | HTR2A (0.52) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| SCHEMBL9409417 | 0.81 | HRH3 (0.52) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| SCHEMBL9409541 | 0.81 | PDE4B (0.46) | HTR2ADRD3DRD2LMNAKDM4E | |
| SCHEMBL9415854 | 0.78 | ALDH1A1 (0.46) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| SCHEMBL9409367 | 0.78 | ALDH1A1 (0.46) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409523 | 0.78 | ALDH1A1 (0.46) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9409352 | 0.78 | ALDH1A1 (0.46) | HTR2ADRD3DRD2MAPTALDH1A1 | |
| SCHEMBL4181896 | 0.74 | HDAC4 (0.57) | ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |