Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639081 | 0.83 | CYP1A1 (0.52) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL5230830 | 0.78 | CA2 (0.51) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL8677605 | 0.77 | ALDH1A1 (0.61) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL5728563 | 0.77 | MAPT (0.61) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL11925422 | 0.71 | KDM4E (0.70) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL29525161 | 0.71 | HSD17B10 (0.67) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1834873 | 0.71 | KDM4E (0.61) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL1598809 | 0.71 | HSD17B10 (0.67) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1959903 | 0.70 | KDM4E (0.55) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL5234936 | 0.70 | CA2 (0.53) | KDM4EHPGDHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630895-A1 | 4-Bicyclic substituted dihydropyridines, process for their preparation and their use in medicaments | BAYER AG (DE) | 1994-12-28 | — | — | EP | disclosed |