Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418797 | 0.82 | POLB (0.40) | POLBKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL27703251 | 0.81 | POLB (0.39) | POLBHSD17B10KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3672729 | 0.79 | KDM4E (0.37) | POLBHSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL10804734 | 0.79 | HPGD (0.41) | POLBHSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL9533816 | 0.78 | KDM4E (0.36) | POLBHSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL14486887 | 0.78 | MAPT (0.37) | HSD17B10KDM4EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4607918 | 0.78 | KDM4E (0.36) | POLBHSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL9026030 | 0.77 | KMT2A (0.34) | HSD17B10KDM4EHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL28341914 | 0.76 | KMT2A (0.40) | POLBHSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL14165763 | 0.76 | LMNA (0.35) | HSD17B10KDM4EHPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699571-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-09-05 | — | — | EP | disclosed |
| EP-0595151-A2 | Imidazopyridine derivates as antagonists of angiotensin II | MERCK PATENT GmbH (DE) | 1994-05-04 | — | — | EP | disclosed |