Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087209 | 0.70 | HIPK2 (0.34) | ALDH1A1SMN1; SMN2HIPK2 | |
| SCHEMBL1651153 | 0.67 | MKNK1 (0.40) | — | |
| SCHEMBL11102592 | 0.62 | CA12 (0.41) | HIPK2TAAR1NISCH | |
| Hydrochloric Acid SCHEMBL28135912 | 0.61 | ALDH1A1 (0.94) | ALDH1A1SMN1; SMN2HIPK2TAAR1NISCH | |
| SCHEMBL114028 | 0.60 | HIPK2 (0.41) | ALDH1A1SMN1; SMN2HIPK2TAAR1NISCH | |
| SCHEMBL23749804 | 0.60 | RAB9A (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16884990 | 0.59 | — | — | |
| SCHEMBL308284 | 0.59 | F2RL1 (0.41) | ALDH1A1SMN1; SMN2HIPK2 | |
| SCHEMBL21240968 | 0.58 | BRD4 (0.42) | ALDH1A1SMN1; SMN2NISCHBRD4 | |
| SCHEMBL3582119 | 0.58 | HIPK2 (0.36) | ALDH1A1SMN1; SMN2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595151-A2 | Imidazopyridine derivates as antagonists of angiotensin II | MERCK PATENT GmbH (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0574846-A2 | Imidazopyridines as angiotensin II antagonistes | MERCK PATENT GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |