SCHEMBL9410342

SCHEMBL9410342

CC(c1ccccc1)N1C(=O)C2CC2(c2ccccc2)C1=O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.57
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.39
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
OPRL1 P41146 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079959 0.87 CYP19A1 (0.74) CYP19A1ALDH1A1HPGDCYP2D6
SCHEMBL11078445 0.75 CYP19A1 (0.71) CYP19A1ALDH1A1
SCHEMBL11463156 0.71 CYP19A1 (0.48) CYP19A1ALDH1A1KMT2A
SCHEMBL8968925 0.71 CYP19A1 (0.82) CYP19A1ALDH1A1KMT2A
SCHEMBL11081758 0.69 CYP19A1 (0.76) CYP19A1ALDH1A1
SCHEMBL8969269 0.69 CYP19A1 (0.62) CYP19A1ALDH1A1KMT2A
SCHEMBL10532357 0.69 CYP19A1 (0.67) CYP19A1ALDH1A1HPGDKMT2A
SCHEMBL9410346 0.69 CYP19A1 (0.64) CYP19A1ALDH1A1HPGD
SCHEMBL14382338 0.67 GAA (0.43) ALDH1A1HPGDKMT2AOPRM1OPRK1
SCHEMBL40439 0.66 ALDH1A1 (0.53) ALDH1A1HPGDKMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5352655-A Pre- and postemergence; rice MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-04 US disclosed
EP-0600507-A1 3-Azabicyclo(3.1.0.)hexane-2-one derivatives and Herbicidal Compositions Containing them as Herbicidally Active Ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed