Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 13/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540992 | 0.79 | AGTR2 (0.44) | AGTR2AGTR1 | |
| SCHEMBL8978466 | 0.78 | AGTR2 (0.44) | AGTR2AGTR1KMT2ALRRK2 | |
| SCHEMBL8549721 | 0.76 | AGTR2 (0.44) | AGTR2AGTR1 | |
| SCHEMBL8593552 | 0.74 | ADRB3 (0.45) | AGTR2 | |
| SCHEMBL9410790 | 0.73 | AGTR2 (0.40) | AGTR2AGTR1MAOBABCB1HTR1A | |
| SCHEMBL8545450 | 0.71 | AGTR2 (0.40) | AGTR2AGTR1DRD2 | |
| SCHEMBL8541940 | 0.68 | KDM1A (0.43) | AGTR2AGTR1MAOB | |
| SCHEMBL9410814 | 0.68 | MAOB (0.36) | AGTR2AGTR1MAOBABCB1HTR1A | |
| SCHEMBL2580244 | 0.67 | MAOB (0.55) | MAOBABCB1HTR1ADRD2KMT2A | |
| SCHEMBL30863337 | 0.66 | KMT2A (0.61) | MAOBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608568-A1 | Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents | AMERICAN CYANAMID COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |