Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540992 | 0.91 | AGTR2 (0.44) | ADRB3ADRB1AGTR2 | |
| SCHEMBL8545450 | 0.80 | AGTR2 (0.40) | AGTR2 | |
| SCHEMBL8978466 | 0.80 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL5142061 | 0.77 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL9410787 | 0.74 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL8548581 | 0.74 | CA1 (0.47) | AGTR2 | |
| SCHEMBL8549721 | 0.74 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL9410814 | 0.73 | MAOB (0.36) | AGTR2 | |
| SCHEMBL10529361 | 0.71 | ADRB3 (0.58) | ADRB3ADRB1 | |
| SCHEMBL10530481 | 0.71 | ADRB3 (0.63) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608568-B1 | Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents | AMERICAN CYANAMID CO (US) | 1998-03-11 | — | — | EP | disclosed |
| US-5594027-A | TREATMENT OF DIABETES, HYPERGLYCEMIA AND OBESITY | AMERICAN CYANAMID COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0608568-A1 | Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents | AMERICAN CYANAMID COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |