Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9411356 | 0.94 | ACHE (0.45) | ACHEMAOBHRH1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9411360 | 0.94 | ACHE (0.45) | ACHEMAOBHRH1MEN1KMT2A | |
| SCHEMBL9411434 | 0.92 | MAOA (0.46) | ACHECCR3MAOBHRH1MAOA | |
| SCHEMBL9411391 | 0.91 | ACHE (0.58) | ACHEMAOB | |
| SCHEMBL9411638 | 0.90 | HTR1A (0.43) | ACHE | |
| SCHEMBL9411377 | 0.88 | ACHE (0.49) | ACHECCR3 | |
| SCHEMBL9411236 | 0.86 | MAOA (0.45) | ACHECCR3MAOBHRH1MAOA | |
| Fumaric Acid SCHEMBL9411463 | 0.86 | ACHE (0.45) | ACHEMAOBHRH1MAOAMEN1 | |
| Fumaric Acid SCHEMBL9411459 | 0.86 | ACHE (0.45) | ACHEMAOBHRH1MAOAMEN1 | |
| SCHEMBL9411647 | 0.82 | ACHE (0.53) | ACHEMAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | claimed |
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |