Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411420 | 0.89 | SLC6A4 (0.52) | ACHESLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL9411647 | 0.85 | ACHE (0.53) | ACHEMEN1KMT2A | |
| SCHEMBL9411661 | 0.85 | ACHE (0.47) | ACHESLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL9411393 | 0.83 | SLC6A4 (0.50) | ACHESLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL9411487 | 0.83 | OPRM1 (0.48) | ACHESLC6A4SLC6A3KDM4EHTR2A | |
| SCHEMBL9411434 | 0.81 | MAOA (0.46) | ACHEMEN1KMT2A | |
| SCHEMBL9411382 | 0.78 | OPRM1 (0.44) | ACHENPC1RAB9ASMN1; SMN2HTR2A | |
| SCHEMBL9411391 | 0.77 | ACHE (0.58) | ACHERAB9A | |
| Fumaric Acid SCHEMBL9411463 | 0.75 | ACHE (0.45) | ACHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL9411459 | 0.75 | ACHE (0.45) | ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |