Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411590 | 0.95 | ACHE (0.46) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411412 | 0.87 | ACHE (0.61) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411656 | 0.85 | HTR1A (0.54) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411320 | 0.85 | ACHE (0.58) | ACHEBCHEDRD2HTR2AHTR6 | |
| SCHEMBL9411603 | 0.85 | ACHE (0.50) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411462 | 0.83 | SLC6A2 (0.57) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411575 | 0.83 | SLC6A4 (0.57) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411545 | 0.83 | ACHE (0.57) | ACHEDRD2HTR2AHTR6 | |
| SCHEMBL9411298 | 0.83 | HTR2A (0.51) | ACHEHTR1ADRD2HTR2AHRH3 | |
| SCHEMBL9411212 | 0.82 | DRD2 (0.52) | ACHEHTR1ADRD2HTR2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |