Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.54 |
| ▸ | DRD2 | P14416 | 11/20 | 0.54 |
| ▸ | HTR2A | P28223 | 11/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411298 | 0.95 | HTR2A (0.51) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411496 | 0.95 | HTR1A (0.55) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411412 | 0.94 | ACHE (0.61) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411603 | 0.93 | ACHE (0.50) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411577 | 0.90 | HTR1A (0.53) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411646 | 0.90 | DRD2 (0.56) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411462 | 0.90 | SLC6A2 (0.57) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411659 | 0.88 | HTR1A (0.51) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411432 | 0.85 | ACHE (0.46) | HTR1ADRD2HTR2AHRH3ACHE | |
| SCHEMBL9411323 | 0.85 | SLC6A2 (0.54) | HTR1ADRD2HTR2AHRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |