Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214262 | 0.81 | ALDH1A1 (0.50) | MAPTRAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL22185265 | 0.75 | HSP90AA1 (0.42) | MAPTRAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL23507084 | 0.73 | MKNK1 (0.47) | MAPTRAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL14516990 | 0.73 | RAB9A (0.51) | RAB9ACYP11B2PTGS2GRM1XDH | |
| SCHEMBL11559004 | 0.68 | ALDH1A1 (0.49) | RAB9ACYP11B2PTGS2DUSP3PTPN5 | |
| SCHEMBL9412158 | 0.67 | HSD11B1 (0.32) | PTGS2 | |
| SCHEMBL13985485 | 0.66 | RAB9A (0.51) | RAB9ACYP11B2PTGS2GRM1XDH | |
| SCHEMBL17055717 | 0.66 | FGFR1 (0.54) | RAB9AFGFR1 | |
| SCHEMBL18500656 | 0.65 | CYP3A4 (0.54) | MAPTRAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL6609392 | 0.65 | MAPKAPK2 (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599183-A1 | Manufacturing of pesticides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1994-06-01 | — | — | EP | claimed |