Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093318 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9412493 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8579118 | 0.76 | DAO (0.58) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7761656 | 0.76 | KMT2A (0.61) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8578124 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8577647 | 0.74 | DAO (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1958344 | 0.74 | MEN1 (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9412738 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7969932 | 0.73 | MTNR1A (0.76) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6093649 | 0.72 | KDM4E (0.80) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |