Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412644 | 0.91 | PDE3B (0.35) | HDAC6HDAC1RECQLALDH1A1ACSS2 | |
| Bromide SCHEMBL9412485 | 0.81 | PDE3B (0.50) | HDAC6ITGB3ITGA2BNPY1R | |
| Bromide SCHEMBL9412756 | 0.80 | CNR2 (0.43) | HDAC6HDAC1HDAC3PTGS1HDAC4 | |
| Bromide SCHEMBL9412454 | 0.79 | HDAC6 (0.40) | HDAC6HDAC1HDAC3PTGS1HDAC4 | |
| Bromide SCHEMBL9412596 | 0.76 | HDAC1 (0.45) | HDAC6HDAC1HDAC3PTGS1HDAC4 | |
| SCHEMBL9412444 | 0.76 | HDAC6 (0.45) | HDAC6HDAC1HDAC3PTGS1HDAC4 | |
| Bromide SCHEMBL9412526 | 0.75 | HDAC6 (0.44) | HDAC6HDAC1HDAC3PTGS1HDAC4 | |
| SCHEMBL9412499 | 0.72 | PDE3B (0.52) | ITGB3ITGA2BNPY1R | |
| SCHEMBL9412497 | 0.72 | CNR2 (0.42) | MEN1RECQLKMT2AALDH1A1ACSS2 | |
| SCHEMBL9188544 | 0.71 | ITGB3 (0.57) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |