Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 12/20 | 0.52 |
| ▸ | PDE2A | O00408 | 6/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9412485 | 0.91 | PDE3B (0.50) | PDE3BPDE3AP2RY12PDE2AITGB3 | |
| SCHEMBL9412582 | 0.86 | PDE3B (0.38) | PDE3BPDE3AP2RY12PDE2AITGB3 | |
| SCHEMBL9412497 | 0.83 | CNR2 (0.42) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL9412644 | 0.82 | PDE3B (0.35) | PDE3BPDE3AP2RY12PDE2ANPY1R | |
| SCHEMBL9412536 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL9412664 | 0.81 | PDE3B (0.42) | PDE3BPDE3AP2RY12PDE2AITGB3 | |
| SCHEMBL9412511 | 0.78 | MAPT (0.45) | ITGB3ITGA2B | |
| Bromide SCHEMBL9412454 | 0.76 | HDAC6 (0.40) | PDE3BPDE3AP2RY12PDE2AITGB3 | |
| SCHEMBL9412731 | 0.76 | KDM4E (0.52) | — | |
| SCHEMBL9412623 | 0.76 | MAPT (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |