Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412490 | 0.91 | HDAC6 (0.40) | ALDH1A1NPY1RHDAC1HDAC6ACSS2 | |
| SCHEMBL9412499 | 0.82 | PDE3B (0.52) | PDE3BPDE3AP2RY12PDE2ANPY1R | |
| SCHEMBL9412497 | 0.82 | CNR2 (0.42) | PDE3BPDE3AP2RY12PDE2AALDH1A1 | |
| SCHEMBL9412582 | 0.81 | PDE3B (0.38) | PDE3BPDE3AP2RY12PDE2AACACB | |
| SCHEMBL9412536 | 0.78 | ITGB3 (0.46) | ACSS2 | |
| SCHEMBL9412664 | 0.78 | PDE3B (0.42) | PDE3BPDE3AP2RY12PDE2AALDH1A1 | |
| SCHEMBL9412511 | 0.75 | MAPT (0.45) | LMNA | |
| SCHEMBL9412731 | 0.74 | KDM4E (0.52) | ALDH1A1RECQL | |
| SCHEMBL9412691 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRCNR2RECQL | |
| Bromide SCHEMBL9412485 | 0.73 | PDE3B (0.50) | PDE3BPDE3AP2RY12PDE2ANPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |