Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412610 | 0.86 | DPP4 (0.50) | GDASTAT3DPP4KDRAURKB | |
| SCHEMBL887125 | 0.81 | GDA (0.55) | GDASTAT3KDRAURKBNEK2 | |
| SCHEMBL9412617 | 0.80 | GDA (0.39) | GDASTAT3DPP4KDRAURKB | |
| SCHEMBL9412633 | 0.78 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL4777463 | 0.77 | GDA (0.42) | GDASTAT3KDRAURKBNEK2 | |
| SCHEMBL12841391 | 0.74 | STAT3 (0.47) | STAT3NEK2L3MBTL1 | |
| SCHEMBL377763 | 0.73 | CDK2 (0.48) | GDADPP4NEK2XDHCDK2 | |
| SCHEMBL1358803 | 0.71 | SYK (0.46) | GDASTAT3KDRAURKBSYK | |
| SCHEMBL8718988 | 0.70 | SYK (0.46) | GDASTAT3KDRAURKBSYK | |
| SCHEMBL16147027 | 0.70 | ADORA3 (0.54) | NEK2SYKXDHCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590361-A1 | Process for the preparation of 2-amino-6-halopurines | BASF Aktiengesellschaft (DE) | 1994-04-06 | — | — | EP | disclosed |