Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413794 | 0.86 | LMNA (0.30) | LMNA | |
| SCHEMBL9413772 | 0.73 | CDK9 (0.33) | — | |
| SCHEMBL9413883 | 0.72 | CSNK2A2 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL9413917 | 0.70 | TSHR (0.32) | AKR1B10 | |
| SCHEMBL9413835 | 0.68 | KMT2A (0.33) | KDM4EALDH1A1 | |
| SCHEMBL9413841 | 0.63 | NOS2 (0.31) | — | |
| SCHEMBL9413839 | 0.62 | PTGS2 (0.33) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9409258 | 0.61 | KMT2A (0.45) | LMNAKDM4EALDH1A1 | |
| SCHEMBL9413872 | 0.61 | — | — | |
| SCHEMBL19086956 | 0.60 | LMNA (0.68) | LMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582261-A1 | Cephalosporin compounds and processes for the preparation thereof | LUCKY LTD. (KR) | 1994-02-09 | — | — | EP | disclosed |