Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 9/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLG | P54098 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901757 | 0.93 | MEN1 (0.57) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL8448753 | 0.81 | MEN1 (0.57) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL7778377 | 0.81 | PDE3A (0.54) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL9414135 | 0.76 | MEN1 (0.52) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL4910722 | 0.75 | MEN1 (0.65) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL13928911 | 0.75 | MEN1 (0.65) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL9022983 | 0.75 | MEN1 (0.64) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL13916680 | 0.74 | MEN1 (0.61) | HPRT1MEN1KMT2AHBBMAPK1 | |
| SCHEMBL4901750 | 0.74 | MEN1 (0.54) | HPRT1MEN1KMT2AHBBMAPK1 | |
| Hydrochloric Acid SCHEMBL9027278 | 0.74 | HBB (0.64) | HPRT1MEN1KMT2AHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596542-A1 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-05-11 | — | — | EP | disclosed |
| US-5061708-A | TREATMENT OF INFECTION BY HERPES OR CYTOMEGALO VIRUS | BURROUGHS WELLCOME CO. (US) | 1991-10-29 | — | — | US | disclosed |