Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HBB | P68871 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.56 |
| ▸ | PNP | P00491 | 10/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414136 | 0.93 | HPRT1 (0.54) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL8448753 | 0.88 | MEN1 (0.57) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL7778377 | 0.88 | PDE3A (0.54) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL13928911 | 0.79 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL4910722 | 0.79 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL14986937 | 0.77 | MEN1 (0.62) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL7778380 | 0.77 | HINT1 (0.40) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL4901750 | 0.76 | MEN1 (0.54) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL13916680 | 0.76 | MEN1 (0.61) | MEN1KMT2AHBBMAPK1HPRT1 | |
| SCHEMBL9740943 | 0.76 | PNP (0.67) | MEN1KMT2AHBBMAPK1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281099-A1 | PROCESS FOR PURIFYING VALACYCLOVIR HYDROCHLORIDE AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES, INC. | 2008-11-13 | — | — | US | claimed |
| US-20080281099-A1 | PROCESS FOR PURIFYING VALACYCLOVIR HYDROCHLORIDE AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES, INC. | 2008-11-13 | — | — | US | disclosed |
| EP-0804436-B1 | GUANINE DERIVATIVE | WELLCOME FOUND (GB) | 2005-08-24 | — | — | EP | disclosed |
| EP-0874631-B1 | USE OF VALACICLOVIR FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF GENITAL HERPES BY A SINGLE DAILY APPLICATION | GLAXO GROUP LTD (GB) | 2003-11-19 | — | — | EP | disclosed |
| US-6107302-A | STORAGE STABLE VALACICLOVIR IN ANHYDROUS CRYSTALLINE FORM; VIRICIDE AGAINST HERPES VIRUS | GLAXO WELLCOME INC. (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0806943-B1 | VALACICLOVIR TABLETS CONTAINING COLLOIDAL SILICON DIOXIDE | WELLCOME FOUND (GB) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281099-A1 | PROCESS FOR PURIFYING VALACYCLOVIR HYDROCHLORIDE AND INTERMEDIATES THEREOF | TYMP, IMPDH1, UMPS | MEN1 2205/4885KMT2A 1845/4885HBB 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.