SCHEMBL9414342

SCHEMBL9414342

CCCCCC1=CCC(COS(=O)(=O)c2ccccc2C)CC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
NPC1 O15118 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR6 P50406 1/20 0.32
MEN1 O00255 2/20 0.31
ESR1 P03372 2/20 0.31
KMT2A Q03164 2/20 0.31
ESR2 Q92731 2/20 0.31
GAA P10253 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
ATM Q13315 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9414343 0.83 CNR1 (0.36) ALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL7739458 0.82 MEN1 (0.39) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL9414344 0.80 ALDH1A1 (0.34) ALDH1A1ESR2LMNAMAPTNPSR1
SCHEMBL9188007 0.78 HTR6 (0.38) ALDH1A1HTR6LMNAMAPTNPSR1
SCHEMBL7070228 0.73 PKM (0.42) ALDH1A1HTR6MEN1ESR1KMT2A
SCHEMBL7067621 0.73 MEN1 (0.40) ALDH1A1SMN1; SMN2HTR6MEN1ESR1
SCHEMBL874690 0.70 CA1 (0.43) ALDH1A1TSHRMEN1ESR1KMT2A
SCHEMBL2417827 0.69 CA1 (0.44) ALDH1A1TSHRMEN1ESR1KMT2A
SCHEMBL7545491 0.69 CA1 (0.44) ALDH1A1TSHRMEN1ESR1KMT2A
SCHEMBL11779434 0.69 CA1 (0.44) ALDH1A1TSHRMEN1ESR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582489-A1 Ferroelectric liquid crystal compounds with cyclohexenyl cores and compositions containing them DISPLAYTECH, INCORPORATED (US) 1994-02-09 EP disclosed
US-5271864-A Ferroelectric liquid crystal compounds with cyclohexenyl cores and compositions containing them DISPLAYTECH, INC. (US) 1993-12-21 US disclosed