SCHEMBL9414540

SCHEMBL9414540

c1ccc(COc2ccccc2Cc2ncc[nH]2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.61
HTR1A P08908 4/20 0.51
DRD2 P14416 3/20 0.51
ABCB1 P08183 3/20 0.51
ADRA2A P08913 1/20 0.51
ADRA2B P18089 1/20 0.51
ADRA2C P18825 1/20 0.51
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
NISCH Q9Y2I1 1/20 0.49
PDE9A O76083 1/20 0.46
PDE1A P54750 1/20 0.46
PDE1B Q01064 1/20 0.46
PDE1C Q14123 1/20 0.46
LTA4H P09960 1/20 0.45
MAPK14 Q16539 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946452 0.86 TAAR1 (0.44) TAAR1HTR1ADRD2ABCB1ADRA2A
SCHEMBL10944433 0.84 PARP1 (0.54) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL954052 0.80 ADRA2A (0.55) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL10848795 0.80 L3MBTL1 (0.51) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL28103549 0.79 ADRA2A (0.69) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL11703352 0.78 FABP3 (0.46) TAAR1ADRA2AADRA2BADRA2CPOLB
SCHEMBL11702882 0.78 TAAR1 (0.73) TAAR1MAOAMAOBLTA4HGAA
SCHEMBL10601013 0.77 DRD2 (0.69) HTR1ADRD2ABCB1MAOAMAOB
SCHEMBL9243 0.77 TAAR1 (1.00) TAAR1HTR1AADRA2AADRA2BADRA2C
SCHEMBL10944476 0.77 TBXAS1 (0.51) TAAR1HTR1AADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600315-A1 Use of bentylimidazolyl derivatives as microbiocides for protecting materials BAYER AG (DE) 1994-06-08 EP disclosed