SCHEMBL9414564

SCHEMBL9414564

C[Si](C)(C)OC(=O)COc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.57
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28274159 0.79 ALOX15 (0.63) ALOX15MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL544051 0.79 ALOX15 (0.63) ALOX15MAPTALDH1A1HPGDHSD17B10
Benzene SCHEMBL28258789 0.79 ALOX15 (0.63) ALOX15MAPTALDH1A1HPGDHSD17B10
SCHEMBL9626682 0.78 PTGS2 (0.46) MAPTALDH1A1KDM4ETP53HPGD
SCHEMBL264346 0.78 ALOX15 (0.68) ALOX15MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL28313123 0.77 ALOX15 (0.61) ALOX15MAPTALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL1959413 0.77 ALOX15 (0.61) ALOX15MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL472034 0.76 ALOX15 (0.65) ALOX15MAPTALDH1A1KDM4EHPGD
SCHEMBL28325138 0.76 ALOX15 (0.65) ALOX15MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL80061 0.76 ALOX15 (0.59) ALOX15MAPTHPGDSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110233289-B High-voltage additive, electrolyte containing same and battery 李秀艳 2023-06-20 CN disclosed
EP-0611770-A2 A process for preparing acid halides ELI LILLY AND COMPANY (US) 1994-08-24 EP disclosed
US-5084568-A Process for preparing acid halides ELI LILLY AND COMPANY (US) 1992-01-28 US disclosed
US-5013854-A Process for preparing acid halides ELI LILLY AND COMPANY (US) 1991-05-07 US disclosed
EP-0381451-A1 A process for preparing acid halides ELI LILLY AND COMPANY (US) 1990-08-08 EP disclosed
US-4297516-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed