SCHEMBL9626682

SCHEMBL9626682

C=Cc1ccc(OCC(=O)O[Si](C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.46
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA7 P36544 1/20 0.42
CHRNA4 P43681 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
LMNA P02545 1/20 0.39
NPC1 O15118 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6774718 0.82 PTGS2 (0.65) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL6778438 0.81 GAA (0.62) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL9414564 0.78 ALOX15 (0.57) SMN1; SMN2GAAALDH1A1MAPTKDM4E
SCHEMBL25996745 0.78 CHRNB2 (0.47) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL412718 0.78 MEN1 (0.50) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL6778614 0.78 MAPT (0.61) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL6773900 0.77 CHRNB2 (0.51) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL4346327 0.76 ALOX15 (0.59) SMN1; SMN2ALDH1A1MAPT
SCHEMBL6777976 0.76 CHRNB2 (0.50) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL6773891 0.76 TSHR (0.47) PTGS2CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476865-A1 Resist material and process for forming pattern using the same WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-03-25 EP disclosed