Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414681 | 0.84 | DRD2 (0.51) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL9414716 | 0.80 | CYP3A4 (0.72) | CYP1A2CYP3A4CYP2C9DRD2DRD3 | |
| SCHEMBL9414743 | 0.77 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9681347 | 0.74 | ACHE (0.38) | — | |
| SCHEMBL9414827 | 0.73 | DRD2 (0.46) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL9414888 | 0.72 | CYP1A2 (0.75) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL9414742 | 0.71 | HTR2C (0.51) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL9414685 | 0.71 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL3750412 | 0.71 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12648468 | 0.69 | CYP3A4 (1.00) | CYP1A2CYP3A4CYP2C9DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594877-A1 | Imidazo(1,2-c)quinazoline derivates as antihyper tensives and anti dysurics | NATIONAL SCIENCE COUNCIL (TW) | 1994-05-04 | — | — | EP | claimed |
| US-5158953-A | 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof | NATIONAL SCIENCE COUNCIL (TW) | 1992-10-27 | — | — | US | claimed |
| EP-0594877-A1 | Imidazo(1,2-c)quinazoline derivates as antihyper tensives and anti dysurics | NATIONAL SCIENCE COUNCIL (TW) | 1994-05-04 | — | — | EP | disclosed |
| US-5158953-A | 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof | NATIONAL SCIENCE COUNCIL (TW) | 1992-10-27 | — | — | US | disclosed |