Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94753 | 0.82 | L3MBTL1 (0.38) | ARKMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL10119881 | 0.82 | MEN1 (0.38) | ARMEN1KMT2AMAPK1MAPT | |
| SCHEMBL93848 | 0.82 | ALDH1A1 (0.33) | ARMEN1KMT2AMAPK1MAPT | |
| SCHEMBL95047 | 0.81 | TDP1 (0.37) | ARMEN1KMT2AMAPK1MAPT | |
| SCHEMBL27868606 | 0.77 | ALDH1A1 (0.35) | ARMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL94285 | 0.70 | AR (0.36) | AR | |
| SCHEMBL94947 | 0.68 | AR (0.36) | AR | |
| SCHEMBL94615 | 0.68 | CYP1A2 (0.30) | MAPT | |
| SCHEMBL28311934 | 0.65 | MEN1 (0.51) | ARMEN1KMT2AMAPK1MAPT | |
| SCHEMBL4595703 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459221-A | Thiophene derivatives | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | claimed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | claimed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | claimed |
| CN-102459221-A | Thiophene derivatives | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | AR, NR5A1, SHBG | AR 1/4885MEN1 3677/4885KMT2A 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.