Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416229 | 0.83 | CES2 (0.48) | SRD5A2MAPTKMT2AHDAC1L3MBTL1 | |
| SCHEMBL2705458 | 0.81 | HDAC3 (0.51) | RAB9ASRD5A2MAPTKMT2AHDAC1 | |
| SCHEMBL9790167 | 0.79 | RAB9A (0.45) | RAB9ASRD5A2MAPTKMT2AHDAC1 | |
| SCHEMBL162936 | 0.78 | ALDH1A1 (0.52) | RAB9AMAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL10428977 | 0.78 | PLK1 (0.44) | RAB9AMAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL2108708 | 0.77 | HDAC3 (0.49) | RAB9ASRD5A2MAPTKMT2AHDAC1 | |
| SCHEMBL9416258 | 0.77 | LMNA (0.46) | RAB9AMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4832150 | 0.77 | ALDH1A1 (0.50) | RAB9AMAPTKMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL9416250 | 0.77 | MAPT (0.67) | MAPTKMT2AHDAC1HPGDALDH1A1 | |
| SCHEMBL9416273 | 0.75 | KMT2A (0.39) | RAB9AMAPTKMT2AHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601520-A1 | Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-06-15 | — | — | EP | disclosed |