Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.37 |
| ▸ | ITGAL | P20701 | 6/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416401 | 0.81 | NOTUM (0.41) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416336 | 0.78 | ITGB2 (0.47) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416360 | 0.73 | ALDH1A1 (0.43) | ITGB2ICAM1ITGALMAPTALDH1A1 | |
| SCHEMBL9416333 | 0.73 | PKM (0.45) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416363 | 0.72 | NOTUM (0.37) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416332 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416357 | 0.70 | LMNA (0.35) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416364 | 0.69 | SMN1; SMN2 (0.48) | ITGB2ICAM1ITGALNOTUMMAPT | |
| SCHEMBL9416338 | 0.68 | AURKA (0.36) | ITGB2ICAM1ITGALMAPTALDH1A1 | |
| SCHEMBL9416344 | 0.68 | HTT (0.39) | ITGB2ICAM1ITGALNOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627423-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE AND AGROHORTICULTURAL BACTERICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |