Sulfathiazole

Sulfathiazole

SCHEMBL94165

Nc1ccc(S(=O)(=O)Nc2nccs2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfathiazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
LMNA P02545 4/20 1.00
KDM4E B2RXH2 1/20 1.00
CYP2C9 P11712 1/20 1.00
EDNRA P25101 1/20 1.00
SLC6A4 P31645 1/20 1.00
ADRA1A P35348 1/20 1.00
PRMT6 Q96LA8 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
SMN1; SMN2 Q16637 2/20 0.72
CYP1A2 P05177 1/20 0.65
PKM P14618 5/20 0.63
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ATM Q13315 1/20 0.60
AKT1 P31749 1/20 0.59
CYP2C19 P33261 1/20 0.58
TSHR P16473 2/20 0.57
AURKA O14965 1/20 0.57
DHFR P00374 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfathiazole SCHEMBL30130508 1.00 ALDH1A1 (1.00) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL468436 0.98 ALDH1A1 (0.97) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL2194108 0.98 ALDH1A1 (0.97) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL18425505 0.98 ALDH1A1 (0.97) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL11623928 0.97 ALDH1A1 (0.94) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL11626630 0.97 ALDH1A1 (0.94) ALDH1A1LMNAKDM4ECYP2C9EDNRA
SCHEMBL848949 0.95 ALDH1A1 (0.91) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL28079171 0.95 ALDH1A1 (0.91) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfathiazole SCHEMBL28264889 0.94 ALDH1A1 (0.89) ALDH1A1LMNAKDM4ECYP2C9EDNRA
Sulfadiazine SCHEMBL28117247 0.92 LMNA (0.84) ALDH1A1LMNAKDM4ECYP2C9EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8382 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747215-A1 PYRAZOLE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR Sabic Agri-Nutrients Company (SA) 2026-05-27 EP claimed
WO-2026099762-A1 AMINODITHIOCARBAMATE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR SABIC Agri-Nutrients Company (SA) 2026-05-15 WO claimed
CN-122029140-A Pyrazole derivatives as dual function urease and nitrification inhibitors 沙特基础工业公司农业营养素 2026-05-12 CN claimed
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME KCTECH CO., LTD. (KR) 2026-04-30 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260054287-A1 PASSIVATION COATING ON COPPER METAL SURFACE FOR COPPER WIRE BONDING APPLICATION UNIV NORTH TEXAS (US) 2026-02-26 US claimed
EP-4660176-A1 N-HETEROCYCLIC COMPOUNDS USED AS NITRIFICATION INHIBITOR EuroChem Antwerpen (BE) 2025-12-10 EP claimed
US-20250364276-A1 TUNABLE LOW-COST PASSIVATION COATING FOR FACILITATING FLUXLESS BONDING OF COPPER SOLDER INTERCONNECTS IN FLIP CHIP ASSEMBLY UNIV NORTH TEXAS (US) 2025-11-27 US claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
US-12448339-B2 Nitrification inhibitors to improve fertilizer efficiency SOILGENIC TECHNOLOGIES, LLC (US) 2025-10-21 US claimed
US-4453007-A FORMING CATIONIC SALT AND ANIONIC SALT WITH SEPARATE PORTIONS OF COMPOUND, MIXING, AND COLLECTING PRECIPITATE USV PHARMACEUTICAL CORPORATION (US) 1984-06-05 US claimed
US-4447421-A COMPACTION TO GIVE UNIFORM PARTICLE SIZE AMERICAN CYANAMID COMPANY (US) 1984-05-08 US claimed
US-4348389-A Quinoxaline adducts useful as anthelmintics INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-09-07 US claimed
US-4315931-A MICROBIOCIDES, INFECTIOUS DISEASES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
EP-0041114-A2 Process for the preparation of medicated animal feed supplement AMERICAN CYANAMID COMPANY (US) 1981-12-09 EP claimed
US-4070356-A Manufacture of soluble sulfathiazole MBH CHEMICAL CORPORATION (US) 1978-01-24 US claimed
US-4066754-A VETERINARY MEDICINE RALSTON PURINA COMPANY (US) 1978-01-03 US claimed
US-4044119-A RUMINANTS, NATIVE MILK SOLIDS, DRUG ENTRAPMENT CUTTER LABORATORIES, INC. (US) 1977-08-23 US claimed
US-4011210-A ANTIBACTERIAL SMITHKLINE CORPORATION (US) 1977-03-08 US claimed
US-3960661-A MUTANT BACILLUS SUBTILIS REQUIRING ADENINE FOR GROWTH AJINOMOTO CO., INC. (JA) 1976-06-01 US claimed