Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416662 | 1.00 | HTT (0.61) | HTTMEN1KMT2ANPC1HPGD | |
| SCHEMBL17261410 | 0.84 | SMPD1 (0.61) | HTTMEN1KMT2ANPC1HPGD | |
| SCHEMBL9416534 | 0.82 | MEN1 (0.64) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL9416643 | 0.81 | KDM4E (0.81) | HTTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9416658 | 0.81 | MEN1 (0.61) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL307913 | 0.81 | HTT (0.62) | HTTMEN1KMT2AHPGDBCHE | |
| SCHEMBL6587769 | 0.80 | SMPD1 (0.65) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL4278415 | 0.79 | NPC1 (0.73) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL1029034 | 0.79 | SMPD1 (0.75) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL242563 | 0.79 | MRGPRX4 (0.77) | MEN1KMT2ANPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |