Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176287 | 0.83 | ADRA2C (0.47) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL14236920 | 0.79 | ADRA2C (0.45) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL8613162 | 0.79 | ADRA2C (0.45) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL11815807 | 0.79 | GABRA1 (0.47) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL6761344 | 0.79 | ADRA2C (0.45) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL9287668 | 0.78 | ADRA2B (0.51) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL11034063 | 0.78 | ADRA2B (0.44) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL173300 | 0.77 | GABRA1 (0.56) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL29763626 | 0.77 | GABRA1 (0.56) | ADRA2CADRA2BGABRA1GABRB2MAPT | |
| SCHEMBL9795634 | 0.76 | ADRA2C (0.43) | ADRA2CADRA2BGABRA1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312984-A | Amidation of vinyl chloride with dimethylamine using a supported palladium catalyst | THE B. F. GOODRICH COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5159113-A | Vinyl chloride reacted with carbon monoxide and amine | THE B. F. GOODRICH COMPANY (US) | 1992-10-27 | — | — | US | disclosed |