Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702787 | 0.94 | ADRA2B (0.41) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL30729429 | 0.94 | MAPT (0.45) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL6046931 | 0.94 | MAPT (0.45) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL7757717 | 0.93 | ADRA2B (0.40) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL11874052 | 0.91 | ALDH1A1 (0.46) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| Ammonia Solution, Strong SCHEMBL20481810 | 0.90 | MAPT (0.51) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL176287 | 0.90 | ADRA2C (0.47) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL1173024 | 0.85 | ALDH1A1 (0.47) | ADRA2BADRA2CMAPTMEN1KMT2A | |
| SCHEMBL9423214 | 0.81 | ADRA2B (0.36) | ADRA2BADRA2CGABRA1GABRB2MAPT | |
| SCHEMBL31530697 | 0.80 | MEN1 (0.48) | ADRA2BADRA2CGABRA1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530995-A | Comminuting in an anhydrous solvent; slurrying with stabilizer | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
| US-4405532-A | SLURRY WITH NONAQUEOUS ORGANIC LIQUID | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1983-09-20 | — | — | US | disclosed |