Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416689 | 0.87 | ALDH1A1 (0.35) | KMT2AMEN1HTTTSHRTDP1 | |
| SCHEMBL28179582 | 0.73 | THRB (0.50) | KMT2AMEN1HTTTSHRTDP1 | |
| SCHEMBL8179048 | 0.69 | OPRK1 (0.49) | KMT2AMEN1HTTTSHRALDH1A1 | |
| SCHEMBL71320 | 0.62 | NPSR1 (0.41) | KMT2AMEN1TSHRALDH1A1LMNA | |
| SCHEMBL16111377 | 0.62 | NPSR1 (0.41) | KMT2AMEN1TSHRALDH1A1LMNA | |
| SCHEMBL31369012 | 0.62 | MEN1 (0.38) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL25227832 | 0.60 | FFAR3 (0.70) | KMT2AMEN1HTTTSHRALDH1A1 | |
| SCHEMBL10210598 | 0.60 | FFAR3 (0.70) | KMT2AMEN1HTTTSHRALDH1A1 | |
| SCHEMBL5080920 | 0.60 | MEN1 (0.37) | KMT2AMEN1TSHRALDH1A1HSD17B10 | |
| SCHEMBL9143861 | 0.60 | MEN1 (0.37) | KMT2AMEN1TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |