Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402444 | 0.87 | DGAT1 (0.34) | DGAT1ALDH1A1KCNN4MEN1LMNA | |
| SCHEMBL28668019 | 0.85 | ALDH1A1 (0.40) | DGAT1ALDH1A1KCNN4MEN1LMNA | |
| SCHEMBL9416745 | 0.83 | DGAT1 (0.36) | DGAT1ALDH1A1KCNN4MEN1LMNA | |
| SCHEMBL11496818 | 0.75 | SRC (0.50) | ALDH1A1KCNN4MAPTTSHRSRC | |
| SCHEMBL788497 | 0.73 | DGAT1 (0.42) | DGAT1ALDH1A1KCNN4TSHRKEAP1 | |
| SCHEMBL8096308 | 0.72 | DGAT1 (0.46) | DGAT1ALDH1A1KCNN4MAPTTSHR | |
| SCHEMBL5960637 | 0.71 | ALDH1A1 (0.39) | DGAT1ALDH1A1KCNN4MEN1LMNA | |
| SCHEMBL2463205 | 0.71 | MEN1 (0.42) | DGAT1ALDH1A1KCNN4MEN1LMNA | |
| SCHEMBL194990 | 0.71 | — | — | |
| SCHEMBL12121537 | 0.71 | DGAT1 (0.46) | DGAT1ALDH1A1KCNN4TSHRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046817-A | Method of synthesis of pyrogallol | IMC CHEMICAL GROUP, INC. (US) | 1977-09-06 | — | — | US | claimed |
| US-8846686-B2 | Compounds useful as inhibitors of ATR kinase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130089625-A1 | Compounds Useful as Inhibitors of ATR Kinase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-04-11 | — | — | US | disclosed |
| CN-101475450-B | Method for preparing pyrogallic acid with glyoxaline as gallic acid decarboxylation catalyst | UNIV NANJING FORESTRY | 2011-07-27 | — | — | CN | disclosed |
| CN-101475450-A | Method for preparing pyrogallic acid with glyoxaline as gallic acid decarboxylation catalyst | UNIV NANJING AGRICULTURAL (CN) | 2009-07-08 | — | — | CN | disclosed |
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| US-4092351-A | Method of synthesis of 4,5,6-trihydroxyisophthalic acid | IMC CHEMICAL GROUP, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4046817-A | Method of synthesis of pyrogallol | IMC CHEMICAL GROUP, INC. (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130089625-A1 | Compounds Useful as Inhibitors of ATR Kinase | ATR, CHEK1, MAP3K1 | DGAT1 3586/4885ALDH1A1 3886/4885KCNN4 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.