Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416764 | 0.83 | DGAT1 (0.42) | DGAT1KCNN4ALDH1A1MEN1LMNA | |
| SCHEMBL28668019 | 0.76 | ALDH1A1 (0.40) | DGAT1KCNN4ALDH1A1MEN1LMNA | |
| SCHEMBL9402444 | 0.72 | DGAT1 (0.34) | DGAT1KCNN4ALDH1A1MEN1LMNA | |
| SCHEMBL18269834 | 0.70 | DGAT1 (0.42) | DGAT1KCNN4ALDH1A1 | |
| SCHEMBL21883869 | 0.70 | DGAT1 (0.54) | DGAT1KCNN4ALDH1A1 | |
| SCHEMBL5247176 | 0.70 | DGAT1 (0.37) | DGAT1KCNN4ALDH1A1 | |
| SCHEMBL27699208 | 0.70 | DGAT1 (0.33) | DGAT1KCNN4MEN1LMNAMAPT | |
| SCHEMBL11496818 | 0.67 | SRC (0.50) | KCNN4ALDH1A1MAPT | |
| SCHEMBL20241522 | 0.67 | DGAT1 (0.31) | DGAT1ALDH1A1 | |
| SCHEMBL160191 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |