Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426723 | 0.86 | LMNA (0.56) | MAPTNPSR1MEN1KMT2AHTT | |
| SCHEMBL374160 | 0.86 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AMET | |
| SCHEMBL27941570 | 0.85 | SMN1; SMN2 (0.44) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL15897371 | 0.83 | OPRM1 (0.47) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL10626087 | 0.83 | FPR2 (0.50) | MAPTNPSR1MEN1KMT2AHTT | |
| SCHEMBL2151745 | 0.83 | SMN1; SMN2 (0.51) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL10631026 | 0.82 | SMN1; SMN2 (0.57) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL10627232 | 0.80 | SAE1 (0.47) | MAPTNPSR1MEN1KMT2AHTT | |
| SCHEMBL15688086 | 0.80 | THRB (0.62) | THRBEPHX2METMTORTRPV1 | |
| SCHEMBL10631447 | 0.79 | LMNA (0.57) | MAPTNPSR1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |