Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416717 | 0.86 | MEN1 (0.48) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL22452882 | 0.84 | MEN1 (0.39) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL28107009 | 0.75 | MEN1 (0.41) | LMNAMAPTMEN1S1PR4S1PR1 | |
| SCHEMBL10626087 | 0.73 | FPR2 (0.50) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL25423720 | 0.72 | ALDH1A1 (0.47) | LMNAMAPTMEN1S1PR4S1PR1 | |
| SCHEMBL28840766 | 0.71 | ALDH1A1 (0.43) | LMNAMAPTMEN1S1PR4S1PR1 | |
| SCHEMBL9416859 | 0.71 | KMT2A (0.47) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL13041535 | 0.70 | ALDH1A1 (0.42) | LMNAMAPTMEN1S1PR4S1PR1 | |
| SCHEMBL1510 | 0.70 | OPRM1 (0.58) | OPRM1OPRD1SLC22A1OPRK1SLC6A4 | |
| SCHEMBL30936910 | 0.70 | ALDH1A1 (0.37) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |