Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908450 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL10373252 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL3070503 | 0.69 | KDM4E (0.44) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3070506 | 0.69 | KDM4E (0.44) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4100479 | 0.66 | KMT2A (0.52) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL941085 | 0.64 | KMT2A (0.55) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27943531 | 0.64 | KMT2A (0.55) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9130522 | 0.64 | KDM4E (0.39) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9130518 | 0.64 | KDM4E (0.39) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27674911 | 0.64 | MEN1 (0.34) | GAAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110004000-A1 | Mitotic Kinesin Inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004000-A1 | Mitotic Kinesin Inhibitor | KIF15, KIF5A, KIF5B | GAA 1882/4885MEN1 3155/4885KMT2A 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.