Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509441 | 0.87 | THRB (0.50) | KMT2AMEN1LMNAMAPTHDAC6 | |
| SCHEMBL19034905 | 0.86 | TDP1 (0.61) | KMT2AMEN1LMNAMAPTTHRB | |
| SCHEMBL5297530 | 0.83 | L3MBTL1 (0.62) | KMT2AMEN1LMNATHRBTDP1 | |
| SCHEMBL10490528 | 0.82 | KMT2A (0.50) | PTPN1KMT2AMEN1NR1I2LMNA | |
| SCHEMBL10490472 | 0.82 | KMT2A (0.50) | PTPN1KMT2AMEN1NR1I2LMNA | |
| SCHEMBL3197597 | 0.80 | NPSR1 (0.59) | PTPN1KMT2AMEN1LMNATHRB | |
| SCHEMBL5516797 | 0.80 | L3MBTL1 (0.56) | KMT2AMEN1MAPTTHRBTDP1 | |
| SCHEMBL28760890 | 0.79 | ALDH1A1 (0.51) | PTPN1KMT2AMEN1NR1I2LMNA | |
| SCHEMBL7952997 | 0.79 | KMT2A (0.64) | PTPN1KMT2AMEN1NR1I2LMNA | |
| SCHEMBL14625066 | 0.79 | KMT2A (0.64) | PTPN1KMT2AMEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |