Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496233 | 0.88 | MAPT (0.55) | ALDH1A1MAPTGAAMAPK1NPSR1 | |
| SCHEMBL9068527 | 0.86 | ELANE (0.45) | ALDH1A1MAPTGAAMAPK1MCL1 | |
| SCHEMBL6054565 | 0.85 | EPHX2 (0.44) | ALDH1A1MAPTGAAMAPK1NPSR1 | |
| SCHEMBL9362051 | 0.84 | LMNA (0.43) | ALDH1A1MAPTGAAMAPK1NPSR1 | |
| SCHEMBL8698399 | 0.82 | PTGS1 (0.49) | ALDH1A1MAPTGAAMAPK1NPSR1 | |
| SCHEMBL6054529 | 0.81 | LMNA (0.49) | MAPTGAAHPNALOX15SIRT5 | |
| SCHEMBL6054593 | 0.81 | PTGS1 (0.50) | ALDH1A1MAPTGAAMAPK1NPSR1 | |
| SCHEMBL8767800 | 0.80 | PPARA (0.52) | MAPTCYP1A2CYP2C19 | |
| SCHEMBL6054536 | 0.80 | MAPT (0.51) | ALDH1A1MAPTGAANR1H4VCAM1 | |
| SCHEMBL6054514 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348203-B1 | PHENOLIC THIOETHERS, THEIR PRODUCTION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-02-24 | — | — | EP | claimed |
| US-5084214-A | Compounds for the treatment of artheriosclerosis | SHIONOGI & CO., LTD. (JP) | 1992-01-28 | — | — | US | claimed |
| US-4968710-A | INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | RIKER LABORATORIES, INC. (US) | 1990-11-06 | — | — | US | claimed |
| EP-0348203-A1 | Phenolic thioethers, their production and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-12-27 | — | — | EP | claimed |
| EP-0317165-B1 | DI-t-butylphenols substituted by an alkoxy or benzyloxy group or a benzylthio group | RIKER LABORATORIES INC (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0348203-B1 | PHENOLIC THIOETHERS, THEIR PRODUCTION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-5084214-A | Compounds for the treatment of artheriosclerosis | SHIONOGI & CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5066822-A | Antiallergens | RIKER LABORATORIES, INC (US) | 1991-11-19 | — | — | US | disclosed |
| US-4968710-A | INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | RIKER LABORATORIES, INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0348203-A1 | Phenolic thioethers, their production and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0317165-A1 | DI-t-butylphenols substituted by an alkoxy or benzyloxy group or a benzylthio group | RIKER LABORATORIES, INC. (US) | 1989-05-24 | — | — | EP | disclosed |