Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417886 | 0.88 | L3MBTL1 (0.41) | PPARAMAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL9417949 | 0.87 | PPARA (0.42) | PPARAPTPN1L3MBTL1LMNAKDM4E | |
| SCHEMBL9417761 | 0.86 | NR1H4 (0.42) | PPARAMAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL9417831 | 0.82 | ELANE (0.43) | PPARAMAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL9417832 | 0.78 | NR1H4 (0.49) | L3MBTL1LMNAALDH1A1MAPK1THRB | |
| SCHEMBL9417917 | 0.77 | NR1H4 (0.47) | ALDH1A1MEN1KMT2ATHRBTSHR | |
| SCHEMBL9417928 | 0.76 | NR1H4 (0.44) | L3MBTL1LMNAKDM4EALDH1A1MAPK1 | |
| SCHEMBL9735495 | 0.76 | NR1H4 (0.48) | ALDH1A1MEN1KMT2ATHRBTSHR | |
| SCHEMBL9417877 | 0.76 | LTB4R (0.42) | L3MBTL1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL9417782 | 0.75 | LTB4R (0.43) | L3MBTL1ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294613-A | Benzene derivatives of p-substituted ether and acid or ester | ELI LILLY AND COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |