Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452381 | 0.82 | CYP19A1 (0.42) | HTR2AHTR2CHTR2BCYP19A1 | |
| SCHEMBL11475323 | 0.80 | MT-CO2 (0.46) | — | |
| SCHEMBL11194330 | 0.79 | DDB1 (0.56) | HTR2AHTR2CHTR2BCYP19A1 | |
| SCHEMBL28408881 | 0.76 | HDAC4 (0.42) | — | |
| SCHEMBL21452166 | 0.75 | ADCYAP1R1 (0.42) | — | |
| SCHEMBL23003290 | 0.72 | NR3C1 (0.46) | — | |
| SCHEMBL21452108 | 0.71 | SLC6A2 (0.36) | CYP19A1 | |
| SCHEMBL24807939 | 0.70 | CHRNB4 (0.42) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL24807942 | 0.70 | CHRNB4 (0.42) | CHRNB4CHRNA3HTR2AHTR2CHTR2B | |
| SCHEMBL17197216 | 0.69 | ALDH1A1 (0.40) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5367079-A | Lipoxygenase inhibitors; antiinflammatory agents, antiallergens | ZENECA LIMITED (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0570112-A1 | Cycloalkane derivatives | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |