Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194330 | 0.84 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL21452545 | 0.80 | ADCYAP1R1 (0.47) | ADCYAP1R1FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21452381 | 0.78 | CYP19A1 (0.42) | — | |
| SCHEMBL9419081 | 0.75 | CHRNB4 (0.42) | — | |
| SCHEMBL11475323 | 0.74 | MT-CO2 (0.46) | DDB1CRBN | |
| SCHEMBL25048330 | 0.74 | HCRTR1 (0.42) | ADCYAP1R1FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12876072 | 0.73 | TAS1R3 (0.44) | ADCYAP1R1FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23993603 | 0.73 | TAS1R3 (0.44) | ADCYAP1R1FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14830660 | 0.72 | MGLL (0.44) | ADCYAP1R1TAS1R3TAS1R1TAS1R2HCRTR1 | |
| SCHEMBL21452566 | 0.71 | KDM1A (0.48) | TAS1R3TAS1R1TAS1R2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |