Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.47 |
| ▸ | CYP24A1 | Q07973 | 7/20 | 0.46 |
| ▸ | CYP27A1 | Q02318 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419741 | 0.90 | MIF (0.62) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL630841 | 0.77 | ACHE (0.58) | CYP26A1CYP24A1CYP27A1ACHE | |
| SCHEMBL8991660 | 0.75 | MAOB (0.54) | MIFSMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7517262 | 0.71 | MIF (0.66) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL7158711 | 0.71 | MIF (0.74) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL2872982 | 0.71 | MIF (0.74) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL14061927 | 0.70 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL4975289 | 0.70 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL14137061 | 0.70 | MIF (0.65) | MIFSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL14286892 | 0.70 | ACHE (0.55) | CYP26A1CYP24A1CYP27A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204373-A | Anticholesterol agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-20 | — | — | US | disclosed |