Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801169 | 0.83 | HTR1A (0.50) | MEN1NPC1KMT2AEDNRAHSP90AA1 | |
| SCHEMBL9235115 | 0.83 | SIRT1 (0.47) | MEN1KMT2AMMP2MMP9MMP12 | |
| SCHEMBL323934 | 0.82 | MMP2 (0.67) | MEN1KMT2AMMP2MMP9MMP12 | |
| SCHEMBL5030912 | 0.78 | EDNRA (0.55) | MEN1NPC1KMT2AEDNRAHSP90AA1 | |
| SCHEMBL6932107 | 0.76 | MMP2 (0.70) | MEN1NPC1KMT2AEDNRAMMP2 | |
| SCHEMBL10358495 | 0.74 | KMT2A (0.52) | MEN1NPC1KMT2AEDNRAHSP90AA1 | |
| SCHEMBL21248520 | 0.74 | SIRT1 (0.62) | MEN1NPC1KMT2AEDNRAHSP90AA1 | |
| SCHEMBL9419860 | 0.74 | PTGS1 (0.43) | MEN1NPC1KMT2AEDNRAMMP2 | |
| SCHEMBL13163776 | 0.73 | EDNRA (0.54) | MEN1KMT2AEDNRAHTR1AHTR3A | |
| SCHEMBL30407941 | 0.72 | EDNRA (0.52) | MEN1NPC1KMT2AEDNRAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |