Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323934 | 0.83 | MMP2 (0.67) | MMP2MMP9MMP12MMP1MMP8 | |
| SCHEMBL9419835 | 0.83 | MEN1 (0.49) | MMP2MMP9MMP12MMP8MMP13 | |
| SCHEMBL2209026 | 0.81 | PTGS2 (0.44) | MMP2MMP9MMP12MAPTCXCL8 | |
| SCHEMBL14097981 | 0.81 | MMP2 (0.39) | MMP2MMP9MMP12MAPTCXCL8 | |
| SCHEMBL10622791 | 0.81 | HPGD (0.47) | SIRT1MAPTPTGS2ALDH1A1HPGD | |
| SCHEMBL2888693 | 0.79 | GABRA1 (0.41) | SIRT1MMP2MMP9MMP12TDP1 | |
| SCHEMBL6723569 | 0.79 | CA12 (0.53) | MMP2MMP9MMP12MAPTCXCL8 | |
| SCHEMBL6713912 | 0.79 | CA12 (0.53) | MMP2MMP9MMP12MAPTCXCL8 | |
| SCHEMBL29143247 | 0.79 | SIRT1 (0.47) | SIRT1MMP2MMP9MMP12TDP1 | |
| SCHEMBL2204495 | 0.78 | PTGS2 (0.56) | MMP2MMP9MMP12MAPTCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668270-A2 | 2-Imidazoline-5-ones derivatives as fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1995-08-23 | — | — | EP | disclosed |