Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14998069 | 0.90 | KIF11 (0.56) | KIF11ALDH1A1TSHRCES2CES1 | |
| SCHEMBL16747679 | 0.90 | KIF11 (0.56) | KIF11ALDH1A1TSHRCES2CES1 | |
| SCHEMBL168026 | 0.84 | ALDH1A1 (0.53) | KIF11PAX8CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL10300106 | 0.82 | GRM5 (0.50) | GRM5FFAR1 | |
| SCHEMBL7717366 | 0.82 | GRM5 (0.50) | GRM5FFAR1 | |
| SCHEMBL718949 | 0.82 | GRM5 (0.50) | GRM5FFAR1 | |
| SCHEMBL2830955 | 0.81 | ALDH1A1 (0.59) | KIF11GRM5FFAR1ALDH1A1TSHR | |
| SCHEMBL7699654 | 0.80 | KIF11 (0.52) | KIF11ALDH1A1TSHRCES2CES1 | |
| Chloromethane SCHEMBL27654425 | 0.79 | PAX8 (0.48) | KIF11PAX8CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL10300108 | 0.79 | KIF11 (0.47) | KIF11GRM5CYP1A1CYP1B1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288727-A | Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0500111-A2 | Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |