Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | PDE9A | O76083 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536003 | 0.91 | ALDH1A1 (0.46) | TSHRALDH1A1ARCYP2A6MAOA | |
| SCHEMBL7636229 | 0.87 | GRIA1 (0.52) | TSHRALDH1A1ARCYP2A6MAOA | |
| SCHEMBL8566940 | 0.84 | AR (0.51) | ARSMN1; SMN2GAA | |
| SCHEMBL18411452 | 0.79 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL18406714 | 0.79 | AR (0.54) | TSHRALDH1A1ARSMN1; SMN2HPGD | |
| SCHEMBL17051410 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ARCYP2A6MAOAPDE9A | |
| SCHEMBL20609123 | 0.78 | LMNA (0.47) | TSHRALDH1A1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL27963955 | 0.77 | ESR2 (0.66) | TSHRALDH1A1ARCYP2A6HPGD | |
| SCHEMBL29799042 | 0.77 | ESR2 (0.66) | TSHRALDH1A1ARCYP2A6HPGD | |
| SCHEMBL17955178 | 0.77 | ESR2 (0.37) | TSHRALDH1A1ARKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200194681-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO LTD (KR) | 2020-06-18 | — | — | US | disclosed |
| US-10615348-B2 | Organic light-emitting device | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-04-07 | — | — | US | disclosed |
| US-20190229276-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-07-25 | — | — | US | disclosed |
| US-10043983-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-08-07 | — | — | US | disclosed |
| US-20170141323-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-05-18 | — | — | US | disclosed |
| US-20170025620-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-01-26 | — | — | US | disclosed |
| US-7507830-B2 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | PHARMACORE, INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-6962999-B2 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | PHARMACORE, INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050124808-A1 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | DSM I.P. ASSETS B.V. (NL) | 2005-06-09 | — | — | US | disclosed |
| US-20030100760-A1 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | DSM N.V. (NL) | 2003-05-29 | — | — | US | disclosed |
| EP-0733366-A2 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0470795-B1 | Process for the manufacture of nitriles | ZENECA LTD (GB) | 1995-01-25 | — | — | EP | disclosed |
| EP-0470794-B1 | Process for the preparation of nitriles | ZENECA LTD (GB) | 1995-01-25 | — | — | EP | disclosed |
| US-5155118-A | Administering angiotensin inhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5153197-A | Treatment of hypertension with angiotensin II blocking imidazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| US-5138069-A | Treating hypertension and congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0470795-A1 | Process for the manufacture of nitriles | ZENECA LIMITED (GB) | 1992-02-12 | — | — | EP | disclosed |
| EP-0470794-A1 | Process for the preparation of nitriles | ZENECA LIMITED (GB) | 1992-02-12 | — | — | EP | disclosed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10043983-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CCNE1, CRY2 | TSHR 3796/4885ALDH1A1 2084/4885AR 3051/4885 |
| US-20190229276-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND | CRY1, CCNT1, CCND2 | TSHR 3246/4885ALDH1A1 1544/4885AR 107/4885 |
| US-20170025620-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CCNE1, CRY2 | TSHR 3796/4885ALDH1A1 2084/4885AR 3051/4885 |
| US-20030100760-A1 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | AHR, PAH, DDT | TSHR 2211/4885ALDH1A1 3227/4885AR 810/4885 |
| US-20050124808-A1 | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles | AHR, PAH, DDT | TSHR 2211/4885ALDH1A1 3227/4885AR 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.