Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939252 | 0.76 | ALDH1A1 (0.47) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7950800 | 0.76 | ALDH1A1 (0.47) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL29199108 | 0.72 | TSHR (0.61) | TSHRGAATDP1CTDSP1ALDH1A1 | |
| SCHEMBL2749958 | 0.71 | TSHR (0.73) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL6572035 | 0.71 | TSHR (0.73) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL23207575 | 0.70 | TSHR (0.58) | TSHRTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7709533 | 0.70 | TSHR (0.54) | TSHRGAAALDH1A1KMT2ALMNA | |
| SCHEMBL30862347 | 0.70 | TSHR (0.67) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL873079 | 0.70 | TSHR (0.67) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2051892 | 0.69 | LMNA (0.45) | GAAALDH1A1MEN1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | claimed |