Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 11/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950800 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTGAATSHRMAPK10 | |
| SCHEMBL7948495 | 0.90 | HSD17B2 (0.51) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL7945646 | 0.90 | HSD17B2 (0.51) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL14330215 | 0.80 | GAA (0.50) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL14322755 | 0.80 | GAA (0.50) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL7709533 | 0.79 | TSHR (0.54) | ALDH1A1MAPTGAATSHRKMT2A | |
| SCHEMBL7939260 | 0.77 | TSHR (0.55) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL7950760 | 0.77 | TSHR (0.55) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL9420113 | 0.76 | TSHR (0.46) | ALDH1A1MAPTGAATSHRMEN1 | |
| SCHEMBL7939239 | 0.75 | NR3C1 (0.54) | ALDH1A1GAATSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3159388-B2 | — | — | 2001-04-23 | — | — | JP | claimed |
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | claimed |
| EP-0515622-A1 | ORGANOLEPTIC COMPOSITIONS. | GIVAUDAN ROURE INT (CH) | 1992-12-02 | — | — | EP | claimed |
| US-5144048-A | Dicarboalkoxy dioxolane derivatives | L. GIVAUDAN & CIE, S.A. (CH) | 1992-09-01 | — | — | US | claimed |
| WO-1992010107-A1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-25 | — | — | WO | claimed |
| US-5371069-A | Organoleptic compositions | GIUAUDAN-ROURE CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0515622-B1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN ROURE INT (CH) | 1994-07-20 | — | — | EP | disclosed |
| EP-0515622-A1 | ORGANOLEPTIC COMPOSITIONS. | GIVAUDAN ROURE INT (CH) | 1992-12-02 | — | — | EP | disclosed |
| US-5144048-A | Dicarboalkoxy dioxolane derivatives | L. GIVAUDAN & CIE, S.A. (CH) | 1992-09-01 | — | — | US | disclosed |
| WO-1992010107-A1 | ORGANOLEPTIC COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-25 | — | — | WO | disclosed |